Aspects of Clinical Pharmacology

Image

Journal of Clinical Pharmacology and Toxicology is using Editorial Tracking System to maintain quality and transparency to the author in the peer-review process. Review processing will be performed by the editorial board members of the Journal of Clinical Pharmacology and Toxicology or by Reviewers (outside experts in the field). Two independent reviewer’s approval (Minimum reviewer’s approval) followed by editor approval is obligatory for acceptance of any manuscript excluding an editorial.

Clinical pharmacology is the science of drugs in humans and their optimal clinical use in patients. It is underpinned by the basic science of pharmacology, with an added focus on the application of pharmacological principles and quantitative methods in the real human patient's population. It has a broad scope, from the discovery of new target molecules to the effects of drug usage in whole populations. Clinical Pharmacology promotes the rational use of medications in humans by studying their restorative effect to amplify the drugs effect and reduce the side effects. Clinical pharmacologists bridge the gap between science and the practice of medicine through innovative research, development and regulation of medications. 

Clinical pharmacology also connects the gap between medical practice and laboratory science. The main objective is to promote the safety of prescription, maximize the drug effects and minimize the side effects. In this aspect, there can be an association with pharmacists skilled in areas of drug information, medication safety and other aspects of pharmacy practice related to clinical pharmacology. In fact, in countries such as USA, Netherlands, and France, pharmacists can be trained to become clinical pharmacists, to improve optimal drug therapy with clinical pharmacology related knowledge.

Clinical Pharmacology educates healthcare professionals on a range of topics that involve the interaction between drugs and humans. These topic areas include, but are not limited to, pharmaceutical chemistry, biochemistry, drug metabolism, pharmacokinetics, pharmacodynamics, pharmacometrics, pharmacogenomics, clinical pharmacology practice in the outpatient and inpatient settings, human Pathology, drug interactions and clinical drug trials. 

Clinical pharmacologists are clinicians with training in clinical pharmacology and therapeutics (CPT). Their core goal is to improve patient care through the safe and effective use of medicines.

Clinical pharmacologists enjoy a great deal of diversity throughout their careers. Some choose to focus on a specialist area, but many combine a broad range of work to forge a unique career. Following are the important branches of Pharmacology: Pharmacokinetics, Pharmacodynamics, Therapeutics, Chemotherapy, Pathology, Clinical Pharmacology, Pharmacy, Pharmacognosy, Pharmacogenetics, Pharmacoeconomics, Pharmacoepidemiology, Comparative Pharmacology, Animal Pharmacology, Pharmacoeconomics and Posology.

 

Clinical pharmacology is both old and young. The practice of drug therapy goes back to ancient times and the discovery of drugs such as quinine, reserpine and artemisinin which were first used as herbal medicines. William Withering’s publication on the use of foxglove in the treatment of heart failure may very well be considered the first scientific account of the discipline but it took 200 years before the pharmacology of digitalis was explored with accurate, clinical pharmacological methods. The endeavor of a pharmacologist working in a clinical environment is to develop methods and strategies that improve the quality of drug use in individual patients and patient populations. 

Rational use of drugs implies that drugs should be chosen according to efficacy, ADRs and cost as potentially equally important parameters. Research in clinical pharmacology therefore also includes studies that elicit new data about drugs in use such as new indications and treatment of neglected patient populations. It also includes research into ADRs, Pharmacogenetics and Drug interactions.

On the occasion of its 3 years, Successful Journey, Journal of Clinical Pharmacology and Toxicology decided to provide a partial waiver on its article processing charges to promote quality research from across the nations of the globe to encourage the latest research in the field of Infections, Diseases and Medicine. Journal of Clinical Pharmacology and Toxicology also planning to release a special issue on its new approaches.

Regards

Mary Wilson

Editorial office

Journal of Clinical Pharmacology and Toxicology

E-mail: pharmatoxicol@eclinicalsci.com